Small molecule profiling identifies shared and distinct pathways to non-communicable disease multimorbidity. Pietzner et al., 2020.
Results from Cox-proportional hazard models
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About this matrix
This matrix shows p-values and beta estimates from Cox-proportional hazard models using plasma metabolite levels as the exposure and the risk of 27 diseases (ICD-10 codes) and all-cause mortality (sex-adjusted as well as stratified by sex; >20 years of follow-up).
You can filter/subset the matrix based on statistical criteria, such as association strength or effect estimates, or restricted to an exposure or outcome of interest using the "Settings" menu.
Metabolite name and superpathway (abbrv.)
Trait name and group (abbrv.)
Association between metabolite and traits.
Color: effect size and direction, ranging from -1 (blue) to +1 (red).
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To sort associations, click on a row or column label.
Note: only associations with p < 0.05 in at least one subgroup (all, men, women) are shown.