Cross-platform genetic discovery of small molecule products of metabolism and application to clinical outcomes

Lotta, Pietzner et al. Nature Genetics, 2020 (accepted); preprint available at
Results from this publication are freely available for academic use only (see Licence terms). Contact the corresponding author for non-academic access. Responsibility for the results lies with the corresponding author of this publication. By using these results in your research, you agree to cite our publication. Our legal notice and data protection statement apply. Developed by Johannes Raffler.
Use GRCh37 coordinates on autosomal chromosomes only. Query size maximum is 200kb.
rs ID: 
+/- bp: 
Retrieve association data up to 100kb up- and downstream of the query SNP.
ENSEMBL gene identifier:
Hint: perform a gene id lookup by entering a gene symbol (e.g., FADS1).
By default, associations with pMA ≤ 0.05 for all metabolites are shown. You can adjust the p-value threshold or select metabolites in the advanced options. To enhance the perfomance of queries over a wide genomic range, select a more restrictive p-value threshold and/or limit the number of metabolites.

p-value threshold (meta-analysis)


Meta-analysis (Z-score-based) Fenland INTERVAL Metabolon INTERVAL NMR KORA TwinsUK Draisma EPIC-Norfolk Kettunen